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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8A1
All Species:
18.18
Human Site:
T274
Identified Species:
33.33
UniProt:
Q9Y2Q0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2Q0
NP_006086.1
1164
131369
T274
V
V
Y
T
G
H
D
T
K
L
M
Q
N
S
T
Chimpanzee
Pan troglodytes
XP_001150768
1164
131363
T274
V
V
Y
T
G
H
D
T
K
L
M
Q
N
S
T
Rhesus Macaque
Macaca mulatta
XP_001099138
1164
131392
T274
V
V
Y
T
G
H
D
T
K
L
M
Q
N
S
T
Dog
Lupus familis
XP_849357
1158
131123
T274
V
V
Y
T
G
H
D
T
K
L
M
Q
N
S
T
Cat
Felis silvestris
Mouse
Mus musculus
P70704
1149
129748
N259
L
R
G
A
Q
L
R
N
T
Q
W
V
H
G
I
Rat
Rattus norvegicus
XP_223390
1134
128100
Q249
T
V
P
L
G
A
D
Q
I
L
L
R
G
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518853
932
104820
N54
S
N
V
E
R
I
T
N
I
Q
I
L
I
L
F
Chicken
Gallus gallus
XP_420729
1223
137907
T333
V
V
Y
T
G
H
D
T
K
L
M
Q
N
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666697
916
102033
F38
P
S
S
S
P
P
L
F
H
H
S
N
G
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137649
1324
149578
R433
G
N
D
Q
V
L
Q
R
G
A
I
L
R
N
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200260
1167
132097
I260
M
L
R
N
T
K
W
I
N
A
I
V
I
Y
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XIE6
1213
137734
M278
G
H
E
T
K
V
M
M
N
A
M
N
A
P
S
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
K425
I
F
T
G
H
E
T
K
L
L
R
N
A
T
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.8
96.9
N.A.
95.8
94.5
N.A.
74.4
88.5
N.A.
53.8
N.A.
50.9
N.A.
N.A.
57.6
Protein Similarity:
100
100
100
98
N.A.
97.7
96.3
N.A.
76.9
92.4
N.A.
63.4
N.A.
65.4
N.A.
N.A.
74.8
P-Site Identity:
100
100
100
100
N.A.
0
26.6
N.A.
0
100
N.A.
0
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
13.3
46.6
N.A.
6.6
100
N.A.
13.3
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.2
39.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.6
57.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
0
24
0
0
16
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
47
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
16
0
8
8
47
0
0
0
8
0
0
0
16
8
8
% G
% His:
0
8
0
0
8
39
0
0
8
8
0
0
8
0
0
% H
% Ile:
8
0
0
0
0
8
0
8
16
0
24
0
16
0
8
% I
% Lys:
0
0
0
0
8
8
0
8
39
0
0
0
0
0
0
% K
% Leu:
8
8
0
8
0
16
8
0
8
54
8
16
0
8
0
% L
% Met:
8
0
0
0
0
0
8
8
0
0
47
0
0
0
0
% M
% Asn:
0
16
0
8
0
0
0
16
16
0
0
24
39
8
0
% N
% Pro:
8
0
8
0
8
8
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
8
8
0
8
8
0
16
0
39
0
0
8
% Q
% Arg:
0
8
8
0
8
0
8
8
0
0
8
8
8
0
0
% R
% Ser:
8
8
8
8
0
0
0
0
0
0
8
0
0
39
8
% S
% Thr:
8
0
8
47
8
0
16
39
8
0
0
0
0
8
54
% T
% Val:
39
47
8
0
8
8
0
0
0
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
39
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _